Long COVID Center of Excellence Initiative — Advancing research. Improving Long COVID patient care. · Fund Our Trial Today →
Long COVID Center of Excellence

Researching pathways
to healing.

The Microvascular Research Foundation exists to develop effective, research-based treatment protocols for patients suffering from Long COVID — bringing science and compassion to those left behind.

1,500+
Long COVID patients treated
80%
Significant symptom reduction
2023
Legislative funding secured
1st
Clinical immunofluorescent microscopy in the U.S.
The Microvascular Research Foundation

About MVRF

The Microvascular Research Foundation for Spike Protein and Long COVID was established as a Christian nonprofit organization to offer hope and healing for those suffering from Long COVID and vaccine injury — and to provide novel solutions for the numerous diseases that affect the microvasculature.

Our foundation provides a platform for collaboration among global clinical researchers dedicated to understanding and treating this complex disease. MVRF is home to immunofluorescent microscopes used to research and diagnose microclots — the only ones deployed in a clinical setting in the United States.

In 2023, we obtained legislative funding to support our research and treatment goals. We remain committed to advocacy, individualized patient care, and equipping healthcare providers with expert guidance.

Our Christian Foundation. MVRF was established with Christian values at its core, believing that every individual deserves compassionate care and the opportunity for healing. Our faith guides our commitment to innovative research and patient-centered treatment.

Dr. Jordan Vaughn, Founder and President of MVRF
Dr. Jordan Vaughn
Founder & President, MVRF

Physician and clinical researcher based in Birmingham, Alabama. On the front lines of Long COVID treatment since the earliest days of the pandemic — committed to finding root causes and individualized care for every patient.

Diplomate, American Board of Internal Medicine
  • 1,500+ patients treatedcoordinating individualized Long COVID care
  • First U.S. clinical applicationof immunofluorescent microscopy for microclot diagnosis
  • Legislative funding securedin 2023 to advance MVRF's research goals
Common Questions

Frequently Asked Questions

Understanding Long COVID and how MVRF is working to help.

Long COVID is defined as lingering symptoms of COVID-19 four or more weeks after the initial infection. It often involves multiple body systems and commonly includes chronic fatigue, postexertional malaise, brain fog, shortness of breath, heart rhythm abnormalities, and other neurological symptoms.

Microclots cannot be detected by traditional microscopes or standard D-dimer tests. At MVRF, we use immunofluorescent microscopy — the only clinical application in the U.S. — to diagnose the presence of amyloid fibrin microclots. If you're experiencing Long COVID symptoms, contact our team to explore diagnostic options.

Finding a practitioner who understands Long COVID can be deeply frustrating. MVRF is committed to both treating patients directly and equipping healthcare providers with the latest clinical guidance. Contact our team to learn about access to care or to connect with providers trained in our protocols.

Your donation directly funds clinical research — including our triple anticoagulant therapy trials, Flow Cytometry validation studies, and non-invasive iliac vein treatment research — as well as provider education and patient advocacy efforts.

MVRF is currently enrolling Long COVID patients in a clinical trial testing triple anticoagulant therapy combining repurposed anticoagulant, antiplatelet, and fibrinolytic drugs, along with nutraceuticals thought to aid microclot removal. Contact us to learn about current enrollment opportunities.

Our Mission

Why we're here.

Since 2020, the medical community has been baffled by COVID-19 and Long COVID. In the absence of guidance, many practitioners find themselves unable to grapple with this complicated new disease.

Millions of people are suffering from lingering, debilitating conditions following exposure to the spike protein. Long COVID doesn't discriminate — it impacts individuals of all ages, genders, and abilities.

Patients are tired of being told there's nothing wrong or nothing that can be done. Compassionate practitioners exist, but they need expert guidance. The goal of MVRF is to conduct clinical research that expands access to effective Long COVID treatment and improves patient care.

Our Research Impact

It all begins with microclots.

By understanding the damage microclots cause to small blood vessels, our research has the potential to impact a host of conditions beyond Long COVID.

Long COVID

Millions suffer debilitating symptoms following spike protein exposure. Microclots drive postexertional malaise, fatigue, brain fog, breathing difficulties, and cardiac irregularities. Effective treatments address these by eliminating microclots and restoring vascular health.

Iliac Vein Compression

When microclots compromise an already-compressed iliac vein, blood flow decreases dramatically — causing inflammation, POTS, chronic pain, and in severe cases, the inability to walk. We're pursuing non-invasive treatments more accessible than current surgical options.

Related Microvascular Diseases

Rheumatoid Arthritis, Type 2 Diabetes, Microvascular Cardiac Disease, Alzheimer's, and Parkinson's are all impacted by microclots in small blood vessels. If we can fight microclots in Long COVID, we can fight them in this broader family of diseases.

Current Research

Our Work

Endothelium & Microclot Research
Research Goal

Understanding changes in small vessels with microclots

When spike protein enters the bloodstream, it triggers amyloid fibrin microclots resistant to fibrinolysis. These accumulate, damaging the endothelium and inhibiting oxygen delivery. We are validating Flow Cytometry as a quantitative diagnostic test for amyloid fibrin.

Learn More
Iliac Vein & Vascular Flow
Research Goal

Exploring non-invasive treatments for iliac vein compression

The left iliac vein can be damaged by spike protein-induced vessel wall injury, leaving previously healthy individuals bedbound. Stents exist but require surgery. Through research, we're pursuing accessible, effective non-invasive alternatives for patients.

Learn More
Anticoagulant Clinical Trial
Clinical Trial

Triple therapy for Long COVID patients

Clinicians have observed positive outcomes through triple anticoagulant therapy combining repurposed anticoagulant, antiplatelet, and fibrinolytic drugs — supplemented by nutraceuticals. MVRF is enrolling Long COVID patients to test, validate, and standardize these protocols.

Learn More
Partner With Us

Support the mission.

Help MVRF find effective treatments for Long COVID and related microvascular diseases. Every dollar accelerates research that returns lives to the millions still suffering.

Treatment Impact

Patient stories.

Since 2020, our physicians and researchers have been treating patients with acute and long-term conditions related to Long COVID and spike protein injury.

Hannah Bourgeois
Hannah Bourgeois

"Within days, I felt a difference; within two weeks, I could breathe, speak, and walk normally. These treatments have given me my life back."

Mild COVID in March 2020; became nearly bedridden after a second infection in January 2022. Consulted the Mayo Clinic with no success before coming to MVRF.

James Riley
James Riley

"Within two days of the stent, I was able to walk a mile without pain. I can even go rock climbing now."

Active U.S. Navy; developed severe spreading leg pain within two months of vaccination. Was often crawling to get around before treatment at MVRF.

Henry Ray
Henry Ray

"Dr. Vaughn discovered that microclots were preventing my red blood cells from oxygenating my lungs. With appropriate medication, this condition has improved significantly."

Has both an autoimmune disease and thalassemia. COVID-19 in 2021 triggered microclot formation that standard diagnostic tools could not detect.

Andy Sink
Andy Sink

"My wife says she watched me come back to life with each dose. Dr. Vaughn's team have allowed me to live and thrive today."

Hospitalized with acute COVID in 2021 with a dire prognosis. Left the hospital in extremely poor condition before beginning outpatient triple therapy.

Join the Mission

Get Involved

Partner with MVRF and be a part of the movement to find pathways for healing Long COVID.

Fund Future Research

Donate now to accelerate research and support life-changing treatments for patients suffering from Long COVID.

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Join Our Community

Stay informed. Get the latest news on our research and learn about upcoming volunteer opportunities.

Stay Informed

Contact MVRF

Connect directly with the MVRF team to learn more about our research and how you can get involved or seek care.

Contact Us